Intracellular processing of disease-associated α-synuclein in the human brain suggests prion-like cell-to-cell spread

Dementia with Lewy bodies (DLB), Parkinson’s disease (PD) and multiple system atrophy are characterized by the deposition of disease-associated α-synuclein. In the present study we 1) examined the molecular specificity of the novel anti-α-synuclein 5G4 antibody; 2) evaluated immunoreactivity pattern...

Olles dieđut

Bibliográfalaš dieđut

Váldodahkkit:	Gabor G. Kovacs, Leonid Breydo, Ryan Green, Viktor Kis, Gina Puska, Péter Lőrincz, Laura Perju-Dumbrava, Regina Giera, Walter Pirker, Mirjam Lutz, Ingolf Lachmann, Herbert Budka, Vladimir N. Uversky, Kinga Molnár, Lajos László
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Elsevier 2014-09-01
Ráidu:	Neurobiology of Disease
Fáttát:	α-synuclein endosome ependyma gap junction internalisation lysosome
Liŋkkat:	http://www.sciencedirect.com/science/article/pii/S0969996114001387
Fáddágilkorat:	Lasit fáddágilkoriid Eai fáddágilkorat, Lasit vuosttaš fáddágilkora!