The Deubiquitinating Enzyme Otub2 Modulates Pancreatic Beta-Cells Function and Survival

Background: We have previously demonstrated that ovarian tumor (Otu) domain-containing ubiquitin aldehyde-binding protein 2 (Otub2), a deubiquitinating enzyme, exerts anti-apoptotic effects in primary human islets. The present study aims to further elucidate the molecular mechanis...

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Principais autores:	Michal Oshry, Roi Isaac, Sigalit Boura-Halfon, Estefania Casana, Sanford Sampson, Sima Lev, Fatima Bosch, Yehiel Zick, Yaron Vinik
Format:	Artigo
Jezik:	Inglês
Izdano:	IMR Press 2026-03-01
Serija:	Frontiers in Bioscience-Landmark
Teme:	otub2 pancreatic beta cells nf-κb apoptosis potassium channels
Online dostop:	https://www.imrpress.com/journal/FBL/31/3/10.31083/FBL44406
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