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OTUB1 stabilizes PRRSV matrix protein through a non-canonical deubiquitination mechanism to promote viral replication

ABSTRACT Porcine reproductive and respiratory syndrome virus (PRRSV) poses a major threat to the swine industry worldwide. The viral matrix (M) protein is essential for virion assembly and infectivity. In this study, we found that the M protein is degraded through the ubiquitin-proteasome system. Im...

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Autori principali: Benjin Liu, Wenqi Liang, Xingyu Li, Shan Jiang, Ziqi Shi, Nian Liu, Rongsheng Zhu, Xuanzhi Dong, Han Zhou, Bin Zhou, Jin Cui
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2026-04-01
Serie:Journal of Virology
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Accesso online:https://journals.asm.org/doi/10.1128/jvi.01868-25
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