Cooperation of FGF/MEK/ERK and Wnt/β-catenin pathway regulators to promote the proliferation and pluripotency of mouse embryonic stem cells in serum- and feeder-free conditions

Abstract The FGF/MEK/ERK and Wnt/β-catenin signaling pathways have previously been proved to regulate mouse embryonic stem cell (mESCs) function. However, the relationships between these two pathways, especially their different functions on proliferation and pluripotency of mESCs, were rarely mentio...

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Detalhes bibliográficos

Principais autores:	Tong Zhang, Huanyun Chen, Yiran Zhou, Wanghong Dong, Haibo Cai, Wen-Song Tan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	SpringerOpen 2019-04-01
coleção:	Bioresources and Bioprocessing
Assuntos:	mESCs FGF/MEK/ERK pathway Wnt/β-catenin pathway Small molecule regulator In vitro proliferation
Acesso em linha:	http://link.springer.com/article/10.1186/s40643-019-0249-5
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