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Atrial Natriuretic Peptide Orchestrates a Coordinated Physiological Response to Fuel Non-shivering Thermogenesis

Summary: Atrial natriuretic peptide (ANP) is a cardiac hormone controlling blood volume and pressure in mammals. It is still unclear whether ANP controls cold-induced thermogenesis in vivo. Here, we show that acute cold exposure induces cardiac ANP secretion in mice and humans. Genetic inactivation...

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Автори: Deborah Carper, Marine Coué, Emmani B.M. Nascimento, Valentin Barquissau, Damien Lagarde, Carine Pestourie, Claire Laurens, Justine Vily Petit, Maud Soty, Laurent Monbrun, Marie-Adeline Marques, Yannick Jeanson, Yannis Sainte-Marie, Aline Mairal, Sébastien Déjean, Geneviève Tavernier, Nathalie Viguerie, Virginie Bourlier, Frank Lezoualc’h, Audrey Carrière, Wim H.M. Saris, Arne Astrup, Louis Casteilla, Gilles Mithieux, Wouter van Marken Lichtenbelt, Dominique Langin, Patrick Schrauwen, Cedric Moro
Формат: Artigo
Мова:Inglês
Опубліковано: Elsevier 2020-08-01
Серія:Cell Reports
Предмети:
brown adipose tissue
thermogenesis
uncoupling protein 1
lipolysis
adipocyte
Онлайн доступ:http://www.sciencedirect.com/science/article/pii/S2211124720310603
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