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Integration of Darolutamide in the Treatment Landscape for Metastatic Hormone-sensitive Prostate Cancer: A Systematic Review and Network Meta-analysis of Efficacy and Safety

Background and objective: Recent advances have led to the introduction of multiple combination treatments for metastatic hormone-sensitive prostate cancer (mHSPC), but their comparative efficacy and toxicity remain uncertain owing to the absence of head-to-head comparisons. We evaluated the efficacy...

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Principais autores: Felix Melchior, Magdalena Koett, Felix Keller, Nastasiia Artamonova, Giulia Giannini, Mona Kafka, Michael Ladurner, Hannes Neuwirt, Jasmin Bektic, Wolfgang Horninger, Isabel Heidegger
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2026-01-01
Serier:European Urology Open Science
Fag:
Metastatic hormone-sensitive prostate cancer
Androgen receptor pathway inhibitors
Darolutamide
Doublet therapy
Triplet therapy
Treatment-emergent adverse events
Online adgang:http://www.sciencedirect.com/science/article/pii/S2666168325024760
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