Integration of Darolutamide in the Treatment Landscape for Metastatic Hormone-sensitive Prostate Cancer: A Systematic Review and Network Meta-analysis of Efficacy and Safety

Background and objective: Recent advances have led to the introduction of multiple combination treatments for metastatic hormone-sensitive prostate cancer (mHSPC), but their comparative efficacy and toxicity remain uncertain owing to the absence of head-to-head comparisons. We evaluated the efficacy...

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Principais autores:	Felix Melchior, Magdalena Koett, Felix Keller, Nastasiia Artamonova, Giulia Giannini, Mona Kafka, Michael Ladurner, Hannes Neuwirt, Jasmin Bektic, Wolfgang Horninger, Isabel Heidegger
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2026-01-01
Serija:	European Urology Open Science
Teme:	Metastatic hormone-sensitive prostate cancer Androgen receptor pathway inhibitors Darolutamide Doublet therapy Triplet therapy Treatment-emergent adverse events
Online dostop:	http://www.sciencedirect.com/science/article/pii/S2666168325024760
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