Recurrent Genetic Abnormalities in Human Pluripotent Stem Cells: Definition and Routine Detection in Culture Supernatant by Targeted Droplet Digital PCR

Summary: Genomic integrity of human pluripotent stem cells (hPSCs) is essential for research and clinical applications. However, genetic abnormalities can accumulate during hPSC generation and routine culture and following gene editing. Their occurrence should be regularly monitored, but the current...

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Detalhes bibliográficos

Principais autores:	Said Assou, Nicolas Girault, Mathilde Plinet, Julien Bouckenheimer, Caroline Sansac, Marion Combe, Joffrey Mianné, Chloé Bourguignon, Mathieu Fieldes, Engi Ahmed, Thérèse Commes, Anthony Boureux, Jean-Marc Lemaître, John De Vos
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2020-01-01
coleção:	Stem Cell Reports
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2213671119304436
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