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Generation of four severe early-onset chronic obstructive pulmonary disease (COPD) patient-derived induced pluripotent stem cell lines from peripheral blood mononuclear cells

Evidence highlights the concept of multiple trajectories leading to COPD. Early-life events (i.e., in utero lung development) may influence the maximally attained lung function and increase the risk to develop COPD. Human pluripotent stem cells (hiPSC) represent a unique opportunity to model lung de...

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Principais autores: Engi Ahmed, Mathieu Fieldes, Joffrey Mianné, Chloé Bourguignon, Amel Nasri, Isabelle Vachier, Said Assou, Arnaud Bourdin, John De Vos
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021-10-01
coleção:Stem Cell Research
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1873506121003974
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