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A deoxynucleoside triphosphate triphosphohydrolase promotes cell cycle progression in Caulobacter crescentus

ABSTRACT Intracellular pools of deoxynucleoside triphosphates (dNTPs) are strictly maintained throughout the cell cycle to ensure accurate and efficient DNA replication. DNA synthesis requires an abundance of dNTPs, but elevated dNTP concentrations in nonreplicating cells delay entry into S phase. E...

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Principais autores: Chandler N. Hellenbrand, David M. Stevenson, Katarzyna A. Gromek, Daniel Amador-Noguez, David M. Hershey
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2025-06-01
Serier:Journal of Bacteriology
Fag:
dNTPs
DNA replication
Caulobacter crescentus
cell cycle control
Online adgang:https://journals.asm.org/doi/10.1128/jb.00145-25
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