Aging augments obesity-induced thymic involution and peripheral T cell exhaustion altering the “obesity paradox”

IntroductionThe incidence of obesity, a condition characterized by systemic chronic inflammation, has reached pandemic proportions and is a poor prognostic factor in many pathologic states. However, its role on immune parameters has been diverse and at times contradictory. We have previously demonst...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Logan V. Vick, Craig P. Collins, Lam T. Khuat, Ziming Wang, Cordelia Dunai, Ethan G. Aguilar, Kevin Stoffel, Sai Yendamuri, Randall Smith, Sarbajit Mukherjee, Joseph Barbi, Robert J. Canter, Arta M. Monjazeb, William J. Murphy
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Frontiers Media S.A. 2023-01-01
Sarja:	Frontiers in Immunology
Aiheet:	obesity T cell immunotherapy inflammaging aging thymic involution
Linkit:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.1012016/full
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