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Limited sensitivity of somatosensory evoked potentials as disease monitoring biomarkers in hereditary spastic paraplegias.

<h4>Introduction</h4>Hereditary Spastic Paraplegias (HSP) are a group of genetic disorders leading to the degeneration of long motor and sensory tracts in a progressive course. Clinician-reported outcomes (ClinROs) are the most commonly used endpoints for monitoring these diseases, but they have low...

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Bibliographic Details
Main Authors: Fernando Augusto Marion Spengler, Samanta Ferraresi Brighente, Ana Luiza Rodrigues Louzada, Maria Eduarda Ribeiro de Souza, Isabela Possebon Bevilacqua, Diana Maria Cubillos-Arcila, Jonas Alex Morales Saute
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0335187
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