Domain Requirements and Genetic Interactions of the Mud1 Subunit of the Saccharomyces cerevisiae U1 snRNP

Mud1 is an inessential 298-amino acid protein subunit of the Saccharomyces cerevisiae U1 snRNP. Mud1 consists of N-terminal and C-terminal RRM domains (RRM1 and RRM2) separated by a linker domain. Synthetic lethal interactions of mud1∆ with deletions of inessential spliceosome components Nam8, Mud2,...

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Главные авторы:	Radhika Agarwal, Beate Schwer, Stewart Shuman
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Oxford University Press 2019-01-01
Серии:	G3: Genes, Genomes, Genetics
Предметы:	pre-mRNA splicing U1 snRNP RRM domains mutagenesis synthetic lethality
Online-ссылка:	http://g3journal.org/lookup/doi/10.1534/g3.118.200781
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