Protection against tuberculosis achieved by dissolving microneedle patches loaded with live Mycobacterium paragordonae in a BCG prime-boost strategy

IntroductionSkin vaccination using dissolving microneedle patch (MNP) technology for transdermal delivery is a promising vaccine delivery strategy to overcome the limitations of the existing vaccine administration strategies using syringes. To improve the traditional microneedle mold fabrication tec...

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Auteurs principaux:	Mi-Hyun Lee, Hyejun Seo, Moon-Su Lee, Byoung Jun Kim, Hye Lin Kim, Du Hyung Lee, Jaehun Oh, Ju Yeop Shin, Ju Young Jin, Do Hyeon Jeong, Bum-Joon Kim
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2023-06-01
Collection:	Frontiers in Immunology
Sujets:	Mycobacterium tuberculosis Mycobacterium paragordonae microneedle patch BCG booster vaccine droplet extension method
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1178688/full
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