Engineered probiotic-derived indole-3-propionic acid inhibits ubiquitination via AHR signaling to treat postmenopausal osteoporosis

Postmenopausal osteoporosis (PMOP) has a high incidence in middle-aged and elderly women, leading to an increased risk of fractures and elevated rates of disability and mortality. In this work, we identified the reduction of indole-3-propionic acid (IPA) as a potential key factor contributing to the...

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מידע ביבליוגרפי

Principais autores:	Xueli Qiu, Lijun Wu, Fengxian Jiang, Huajian Shan, Lei Sheng, Bo Tian, Heng Wang, Hao Cui, Lide Tao, Chenyang Wu, Yuqian Yao, Chao Wang, Xiaozhong Zhou, Yingzi Zhang, Jinyu Bai
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Taylor & Francis Group 2026-12-01
סדרה:	Gut Microbes
נושאים:	Postmenopausal osteoporosis gut microbiota indole-3-propionic acid gut-bone axis engineered probiotic
גישה מקוונת:	https://www.tandfonline.com/doi/10.1080/19490976.2025.2612620
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