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Scalable Generation of Mesenchymal Stem Cells and Adipocytes from Human Pluripotent Stem Cells

Human pluripotent stem cells (hPSCs) can provide unlimited supply for mesenchymal stem cells (MSCs) and adipocytes that can be used for therapeutic applications. Here we developed a simple and highly efficient all-<i>trans</i>-retinoic acid (RA)-based method for generating an off-the-shelf and scala...

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Main Authors: Manale Karam, Ihab Younis, Noor R. Elareer, Sara Nasser, Essam M. Abdelalim
Format: Artigo
Language:Inglês
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
retinoic acid
hpscs
mscs
apoptosis
proliferation
rna-seq
adipogenic differentiation
Online Access:https://www.mdpi.com/2073-4409/9/3/710
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