(Dys)regulation of Synaptic Activity and Neurotransmitter Release by β-Amyloid: A Look Beyond Alzheimer's Disease Pathogenesis

Beside its widely studied role in the pathogenesis of Alzheimer's disease (AD), β-amyloid (Aβ) is a normal and soluble product of neuronal metabolism that regulates several key physiological functions, exerting neuromodulatory effects on synaptic plasticity, memory, and neurotransmitter release. Suc...

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Principais autores:	Francesca Fagiani, Cristina Lanni, Marco Racchi, Stefano Govoni
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-02-01
coleção:	Frontiers in Molecular Neuroscience
Assuntos:	β-amyloid Alzheimer's disease synaptic activity neurotransmission neuropsychiatric symptoms synaptic vesicle cycle
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fnmol.2021.635880/full
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