Approach for the Design of Covalent Protein Kinase Inhibitors via Focused Deep Generative Modeling
Deep machine learning is expanding the conceptual framework and capacity of computational compound design, enabling new applications through generative modeling. We have explored the systematic design of covalent protein kinase inhibitors by learning from kinome-relevant chemical space, followed by...
I tiakina i:
| Ngā kaituhi matua: | , , |
|---|---|
| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
MDPI AG
2022-01-01
|
| Rangatū: | Molecules |
| Ngā marau: | |
| Urunga tuihono: | https://www.mdpi.com/1420-3049/27/2/570 |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
|