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Never Gonna Give You Up – Current Developments in Covalent Protein Kinase Inhibitors

Covalent inhibitors have recently seen a revival in medicinal chemistry. Inhibitors addressing non-catalytic cysteine residues with weakly reactive electrophiles have been very successfully employed to target protein kinases, one of the major druggable protein families. Here we provide an overview...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Laura Hillebrand, Matthias Gehringer
Fformat: Artigo
Iaith:Alemão
Cyhoeddwyd: Swiss Chemical Society 2022-05-01
Cyfres:CHIMIA
Pynciau:
Mynediad Ar-lein:https://chimia.ch/chimia/article/view/6037
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!