Turning foes to friends: Advanced “in situ nanovaccine” with dual immunoregulation for enhanced immunotherapy of metastatic triple-negative breast cancer

As a “cold tumor”, triple-negative breast cancer (TNBC) exhibits limited responsiveness to current immunotherapy. How to enhance the immunogenicity and reverse the immunosuppressive microenvironment of TNBC remain a formidable challenge. Herein, an “in situ nanovaccine” Au/CuNDs-R848 was designed fo...

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Autori principali:	Ze Wang, Tong Sha, Jinwei Li, Huanyu Luo, Annan Liu, Hao Liang, Jinbiao Qiang, Lei Li, Andrew K. Whittaker, Bai Yang, Hongchen Sun, Ce Shi, Quan Lin
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	KeAi Communications Co., Ltd. 2024-09-01
Serie:	Bioactive Materials
Soggetti:	Metastatic triple-negative breast cancer In situ nanovaccine Immunogenic cell death Dual immunoregulation Synergistic therapy
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2452199X24001543
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