Integrative bioinformatic and clinical validation reveals dynamic regulation of circulating microRNAs before and after antiretroviral therapy in HIV-positive patients

Abstract MicroRNAs (miRNAs) play a crucial role in gene regulation, including HIV, where they influence viral replication and immune response. This study aims to identify key miRNAs involved in HIV pathogenesis, using bioinformatics and cohort validation to explore their potential as biomarkers for...

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Autors principals:	Haktan Sonmez, Zofia Wicik, Ceren Eyileten, Sara Ahmadova, Ömer Fehmi Tabak, Bilgul Mete, Ilker Inanc Balkan, Oner Suzer, Andleeb Shahzadi
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2025-12-01
Col·lecció:	Scientific Reports
Matèries:	HIV Circulating MicroRNAs Biomarkers MiRNAs Bioinformatics Antiretroviral therapy
Accés en línia:	https://doi.org/10.1038/s41598-025-28055-w
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