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Integrative bioinformatic and clinical validation reveals dynamic regulation of circulating microRNAs before and after antiretroviral therapy in HIV-positive patients

Abstract MicroRNAs (miRNAs) play a crucial role in gene regulation, including HIV, where they influence viral replication and immune response. This study aims to identify key miRNAs involved in HIV pathogenesis, using bioinformatics and cohort validation to explore their potential as biomarkers for...

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Principais autores: Haktan Sonmez, Zofia Wicik, Ceren Eyileten, Sara Ahmadova, Ömer Fehmi Tabak, Bilgul Mete, Ilker Inanc Balkan, Oner Suzer, Andleeb Shahzadi
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Portfolio 2025-12-01
סדרה:Scientific Reports
נושאים:
HIV
Circulating MicroRNAs
Biomarkers
MiRNAs
Bioinformatics
Antiretroviral therapy
גישה מקוונת:https://doi.org/10.1038/s41598-025-28055-w
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