Induced pluripotent stem cell derived pericytes respond to mediators of proliferation and contractility

Abstract Background Pericytes are multifunctional contractile cells that reside on capillaries. Pericytes are critical regulators of cerebral blood flow and blood–brain barrier function, and pericyte dysfunction may contribute to the pathophysiology of human neurological diseases including Alzheimer...

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Detalhes bibliográficos

Principais autores:	Natalie E. King, Jo-Maree Courtney, Lachlan S. Brown, Alastair J. Fortune, Nicholas B. Blackburn, Jessica L. Fletcher, Jake M. Cashion, Jana Talbot, Alice Pébay, Alex W. Hewitt, Gary P. Morris, Kaylene M. Young, Anthony L. Cook, Brad A. Sutherland
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2024-03-01
coleção:	Stem Cell Research & Therapy
Assuntos:	Induced pluripotent stem cells (iPSCs) Pericytes Human brain vascular pericytes (HBVPs) Proliferation Platelet-derived growth factor BB (PDGF-BB) Platelet-derived growth factor receptor β (PDGFRβ)
Acesso em linha:	https://doi.org/10.1186/s13287-024-03671-x
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