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Phosphorylation and oligomerization of α-synuclein associated with GSK-3β activation in the rTg4510 mouse model of tauopathy

Abstract Neurodegenerative diseases are characterized by the accumulation of specific phosphorylated protein aggregates in the brain, such as hyperphosphorylated tau (hp-tau) in tauopathies and phosphorylated α-synuclein (p-αSyn) in α-synucleinopathies. The simultaneous accumulation of different pro...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Yuta Takaichi, James K. Chambers, Hiroyuki Inoue, Yasuhisa Ano, Akihiko Takashima, Hiroyuki Nakayama, Kazuyuki Uchida
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2020-06-01
Rangatū:Acta Neuropathologica Communications
Ngā marau:
Urunga tuihono:http://link.springer.com/article/10.1186/s40478-020-00969-8
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