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p53 regulates DREAM complex-mediated repression in a p21-independent manner

Abstract The DREAM repressor complex regulates genes involved in the cell cycle and DNA repair, vital for maintaining genome stability. Although it mediates p53-driven repression through the canonical p53-p21-Rb axis, the potential for p53 to directly regulate DREAM targets independently of its tran...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Ritu Agrawal, Sagar Sengupta
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Nature 2025-03-01
Schriftenreihe:The EMBO Journal
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Online-Zugang:https://doi.org/10.1038/s44318-025-00402-7
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