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Structure-guided development of an electrochemical aptasensor for Salmonella Typhi HlyE antigen detection using in silico and experimental approaches

Abstract Efficient and timely detection of biomarkers for typhoid fever is pivotal for improving treatment outcomes and preventing further transmission of the disease. This study addresses the pressing need for a rapid and accurate point-of-care test to detect Salmonella Typhi HlyE antigen, a vital...

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Uloženo v:
Hlavní autoři: Mohamad Ahmad Najib, Anja Winter, Khairul Mohd Fadzli Mustaffa, Muhammad Hafiznur Yunus, Eugene Boon Beng Ong, Kasturi Selvam, Muhammad Fazli Khalid, Mohd Syafiq Awang, Asrulnizam Abd Manaf, Yazmin Bustami, Habibah A. Wahab, Ismail Aziah
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2026-02-01
Edice:Scientific Reports
Témata:
Aptamer
Molecular docking
Molecular dynamics
Aptasensor
Salmonella Typhi
On-line přístup:https://doi.org/10.1038/s41598-026-38666-6
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