A strongly selected mutation in the HIV-1 genome is independent of T cell responses and neutralizing antibodies

Abstract Background Mutations rapidly accumulate in the HIV-1 genome after infection. Some of those mutations are selected by host immune responses and often cause viral fitness losses. This study is to investigate whether strongly selected mutations that are not associated with immune responses res...

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Autori principali:	Donglai Liu, Chu Wang, Bhavna Hora, Tao Zuo, Nilu Goonetilleke, Michael K. P. Liu, Mark Berrong, Guido Ferrari, Andrew J. McMichael, Tanmoy Bhattacharya, Alan S. Perelson, Feng Gao
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2017-10-01
Serie:	Retrovirology
Soggetti:	Mutation Selection Immune responses Cryptic T cell response Fitness Escape
Accesso online:	http://link.springer.com/article/10.1186/s12977-017-0371-4
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