Allele-Specific PCR for PIK3CA Mutation Detection Using Phosphoryl Guanidine Modified Primers

Phosphoryl guanidine (PG) is the novel uncharged modification of internucleotide phosphates of oligonucleotides. Incorporating PG modification into PCR primers leads to increased discrimination between wild-type and mutated DNA, providing extraordinary detection limits in an allele-specific real-tim...

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Detaylı Bibliyografya
Asıl Yazarlar:	Alexey S. Chubarov, Igor P. Oscorbin, Lidiya M. Novikova, Maxim L. Filipenko, Alexander A. Lomzov, Dmitrii V. Pyshnyi
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	MDPI AG 2023-01-01
Seri Bilgileri:	Diagnostics
Konular:	mutation detection PIK3CA mutations allele-specific PCR modified oligonucleotides phosphoryl guanidine oligonucleotide
Online Erişim:	https://www.mdpi.com/2075-4418/13/2/250
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Allele-Specific PCR for PIK3CA Mutation Detection Using Phosphoryl Guanidine Modified Primers

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