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T cells from Programmed Death-1 deficient mice respond poorly to Mycobacterium tuberculosis infection.

Programmed Death-1 (PD-1; CD279) receptor molecule is widely believed to be a negative regulator predominantly expressed by exhausted/activated mouse T cells. Upon interaction with its ligands, PD-L1 and PD-L2, PD-1 inhibits activation of T cells and cytokine production, which has been documented in...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sultan Tousif, Yogesh Singh, Durbaka Vijaya Raghava Prasad, Pawan Sharma, Luc Van Kaer, Gobardhan Das
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science (PLoS) 2011-05-01
Cyfres:PLoS ONE
Mynediad Ar-lein:http://europepmc.org/articles/PMC3093409?pdf=render
Tagiau: Ychwanegu Tag
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