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A novel peptide interferes with Mycobacterium tuberculosis virulence and survival

Tuberculosis (TB) is a huge global burden, with new and resistant strains emerging at an alarming rate, necessitating an urgent need for a new class of drug candidates. Here, we report that SL3, a novel 33-amino acid peptide, causes debilitating effects on mycobacterial morphology. Treatment with SL...

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Autores principales: Sachin Kumar Samuchiwal, Sultan Tousif, Dhiraj Kumar Singh, Arun Kumar, Anamika Ghosh, Kuhulika Bhalla, Prem Prakash, Sushil Kumar, Ashish Chandra Trivedi, Maitree Bhattacharyya, Gobardhan Das, Anand Ranganathan
Formato: Artigo
Lenguaje:Inglês
Publicado: Wiley 2014-01-01
Colección:FEBS Open Bio
Materias:
Antimycobacterial peptides
ESAT6
Mycobacterium tuberculosis
Protein–protein interaction
Acceso en línea:http://www.sciencedirect.com/science/article/pii/S2211546314000758
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