CD147 regulates the Rap1 signaling pathway to promote proliferation, migration, and invasion, and inhibit apoptosis in colorectal cancer cells

Abstract The malignant progression of colorectal cancer (CRC) is intimately associated with the abnormal regulation of transmembrane glycoprotein CD147. However, the molecular mechanism via the Rap1/Rap1GAP signaling axis has not been elucidated. This study, through integrated bioinformatics analysi...

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Váldodahkkit:	Fu Xiaoxia, Li Rui, Chen Meiru, Yuan Lu, Jin Ying
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Nature Portfolio 2025-04-01
Ráidu:	Scientific Reports
Fáttát:	Colorectal cancer CD147 Rap1/Rap1GAP signaling pathway Apoptosis Epithelial-mesenchymal transition (EMT)
Liŋkkat:	https://doi.org/10.1038/s41598-025-98266-8
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