Silencing of CD147 inhibits cell proliferation, migration, invasion, lipid metabolism dysregulation and promotes apoptosis in lung adenocarcinoma via blocking the Rap1 signaling pathway

Abstract Objective CD147 is an important glycoprotein that participates in the progression of diverse cancers. This study aims to explore the specific function of CD147 in lung adenocarcinoma (LUAD) and to reveal related downstream molecular mechanisms. Methods Followed by silencing of CD147, the vi...

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Hlavní autoři:	Ning Zhang, Zhouzhong Liu, Xuwang Lai, Shubin Liu, Yuli Wang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2023-10-01
Edice:	Respiratory Research
Témata:	Lung adenocarcinoma CD147 Transcriptome sequencing Lipid metabolism Rap1 signaling pathway
On-line přístup:	https://doi.org/10.1186/s12931-023-02532-0
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