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Epigenetic Classification of Human Mesenchymal Stromal Cells

Standardization of mesenchymal stromal cells (MSCs) is hampered by the lack of a precise definition for these cell preparations; for example, there are no molecular markers to discern MSCs and fibroblasts. In this study, we followed the hypothesis that specific DNA methylation (DNAm) patterns can as...

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Main Authors: Danilo Candido de Almeida, Marcelo R.P. Ferreira, Julia Franzen, Carola I. Weidner, Joana Frobel, Martin Zenke, Ivan G. Costa, Wolfgang Wagner
Format: Artigo
Language:Inglês
Published: Elsevier 2016-02-01
Series:Stem Cell Reports
Subjects:
epigenetic score
mesenchymal stromal cell
mesenchymal stem cell
fibroblast
bone marrow
adipose tissue
DNA methylation
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671116000205
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