Plakoglobin transmits tension across VE-cadherin for vascular leak formation and leukocyte diapedesis

Abstract VE-cadherin controls endothelial junction integrity, and thereby inflammation-induced vascular permeability and leukocyte extravasation. The adhesive function of VE-cadherin is influenced by its binding to β-catenin, which is linked by α-catenin to actin. Plakoglobin can replace β-catenin i...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Neha Uttekar, Annette Artz, Vallari Ghanekar, Pragya Kaul, Jessica Heinrichs, Rebekka I Stegmeyer, Gizem Gülevin Takir, Astrid F Nottebaum, Dietmar Vestweber
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Springer Nature 2026-03-01
Sarja:	The EMBO Journal
Aiheet:	Endothelial Junctions Vascular Permeability Leukocyte Trafficking
Linkit:	https://doi.org/10.1038/s44318-026-00732-0
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