Identification of the HIV-1 Vif and Human APOBEC3G Protein Interface
Human cells express natural antiviral proteins, such as APOBEC3G (A3G), that potently restrict HIV replication. As a counter-defense, HIV encodes the accessory protein Vif, which binds A3G and mediates its proteasomal degradation. Our structural knowledge on how Vif and A3G interact is limited, beca...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2015-12-01
|
| Schriftenreihe: | Cell Reports |
| Online-Zugang: | http://www.sciencedirect.com/science/article/pii/S2211124715012577 |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|