Identification of the HIV-1 Vif and Human APOBEC3G Protein Interface
Human cells express natural antiviral proteins, such as APOBEC3G (A3G), that potently restrict HIV replication. As a counter-defense, HIV encodes the accessory protein Vif, which binds A3G and mediates its proteasomal degradation. Our structural knowledge on how Vif and A3G interact is limited, beca...
Gardado en:
| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Elsevier
2015-12-01
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| Series: | Cell Reports |
| Acceso en liña: | http://www.sciencedirect.com/science/article/pii/S2211124715012577 |
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