Second generation β-elemene nitric oxide derivatives with reasonable linkers: potential hybrids against malignant brain glioma

Elemene is a second-line broad-spectrum anti-tumour drug that has been used in China for more than two decades. However, its main anti-tumour ingredient, β-elemene, has disadvantages, including excessive lipophilicity and relatively weak anti-tumour efficacy. To improve the anti-tumour activity of β...

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Autors principals:	Renren Bai, Junlong Zhu, Ziqiang Bai, Qing Mao, Yingqian Zhang, Zi Hui, Xinyu Luo, Xiang-Yang Ye, Tian Xie
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis Group 2022-12-01
Col·lecció:	Journal of Enzyme Inhibition and Medicinal Chemistry
Matèries:	β-elemene no donor natural product anti-tumour malignant glioma
Accés en línia:	http://dx.doi.org/10.1080/14756366.2021.2016734
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