Cortical oxygen extraction fraction using quantitative BOLD MRI and cerebral blood flow during vasodilation

Introduction: We aimed to demonstrate non-invasive measurements of regional oxygen extraction fraction (OEF) from quantitative BOLD MRI modeling at baseline and after pharmacological vasodilation. We hypothesized that OEF decreases in response to vasodilation with acetazolamide (ACZ) in healthy cond...

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Autori principali:	Linh N. N. Le, Gregory J. Wheeler, Emily N. Holy, Corinne A. Donnay, Nicholas P. Blockley, Alan H. Yee, Kwan L. Ng, Audrey P. Fan
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2023-10-01
Serie:	Frontiers in Physiology
Soggetti:	Oxygen extraction fraction (OEF) cerebral blood flow (CBF) vasodilation arterial spin labeling (ASL) MRI quantitative BOLD (qBOLD) magnetic resonance imaging (MRI)
Accesso online:	https://www.frontiersin.org/articles/10.3389/fphys.2023.1231793/full
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