Mechanism of Substrate Activation by Tryptophan Hydroxylase: A Computational Study

Abstract Serotonin is a hormone that is responsible for mood regultion in the brain; however, details on its biosynthetic mechanism remain controversial. Tryptophan hydroxylase catalyzes the first step in the serotonin biosynthesis in the human body, where it regio‐ and stereoselectively hydroxylate...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Dr. Thirakorn Mokkawes, Dr. Sam P. deVisser
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Wiley-VCH 2025-01-01
Цуврал:	ChemistryEurope
Нөхцлүүд:	Density functional theory Enzyme catalysis Inorganic Reaction Mechanisms Nonheme iron QM Cluster models
Онлайн хандалт:	https://doi.org/10.1002/ceur.202400067
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!