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Mechanism of Substrate Activation by Tryptophan Hydroxylase: A Computational Study

Abstract Serotonin is a hormone that is responsible for mood regultion in the brain; however, details on its biosynthetic mechanism remain controversial. Tryptophan hydroxylase catalyzes the first step in the serotonin biosynthesis in the human body, where it regio‐ and stereoselectively hydroxylate...

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Autori principali: Dr. Thirakorn Mokkawes, Dr. Sam P. deVisser
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley-VCH 2025-01-01
Serie:ChemistryEurope
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Accesso online:https://doi.org/10.1002/ceur.202400067
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