Mechanism of Substrate Activation by Tryptophan Hydroxylase: A Computational Study
Abstract Serotonin is a hormone that is responsible for mood regultion in the brain; however, details on its biosynthetic mechanism remain controversial. Tryptophan hydroxylase catalyzes the first step in the serotonin biosynthesis in the human body, where it regio‐ and stereoselectively hydroxylate...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Wiley-VCH
2025-01-01
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| Serie: | ChemistryEurope |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1002/ceur.202400067 |
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