A liver gene signature links liver cancer risk in chronic viral hepatitis to intrahepatic IgA plasma cells

Background & Aims: Chronic viral hepatitis remains a leading cause of liver cancer-related mortality worldwide. We aimed to identify genetic markers associated with hepatocellular carcinoma (HCC) risk in precancerous liver biopsies from patients with chronic HBV or HCV infection. Methods: We con...

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Autors principals:	Nicolaas Van Renne, Fleur Ballet, Stijn Van Hees, Bart Cuypers, Arno Furquim d’Almeida, Axelle Vanderlinden, Pieter Meysman, Jordan J. Feld, Paloma Sangro del Alcázar, Stefan Bourgeois, Dirk Sprengers, Geert Robaeys, Luisa Vonghia, Peter Michielsen, Sven Francque, Bruno Sangro, Owen Cain, Ahmed M. Elsharkawy, Rob De Man, Andre Boonstra, Harry L.A. Janssen, Ann Driessen, Kris Laukens, Thomas Vanwolleghem
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2026-04-01
Col·lecció:	JHEP Reports
Matèries:	chronic viral hepatitis HCC risk liver transcriptome IgA plasma cells
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2589555925003970
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