Loss of vitamin D receptor induces premature ovarian insufficiency through compromising the 7-dehydrocholesterol-dependent anti-aging effects

Vitamin D has the potential to therapeutically affect the endocrine parameters of premature ovarian insufficiency (POI) patients. Previous research has indicated that serum vitamin D levels tend to decline with age and in individuals with POI. However, the precise impact of vitamin D deficiency on f...

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Autors principals:	Haiyun Chen, Qiuyi Wang, Yi Zhang, Luxi Shangguan, Zhengquan Zhu, Huan Zhang, Xiang Zou, Qinghe Geng, Yanting Wen, Daojuan Wang, Yong Wang
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2025-04-01
Col·lecció:	Frontiers in Cell and Developmental Biology
Matèries:	VDR premature ovarian insufficiency (POI) granulosa cell 7-dehydrocholesterol (7-DHC) aging
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fcell.2025.1545167/full
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