Restriction factor screening identifies RABGAP1L-mediated disruption of endocytosis as a host antiviral defense
Summary: Host interferons (IFNs) powerfully restrict viruses through the action of several hundred IFN-stimulated gene (ISG) products, many of which remain uncharacterized. Here, using RNAi screening, we identify several ISG restriction factors with previously undescribed contributions to IFN-mediat...
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| Principais autores: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2022-03-01
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| Serier: | Cell Reports |
| Fag: | |
| Online adgang: | http://www.sciencedirect.com/science/article/pii/S221112472200290X |
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