Sex differences in the polygenic architecture of hearing problems in adults

Abstract Background Hearing problems (HP) in adults are common and are associated with several comorbid conditions. Its prevalence increases with age, reflecting the cumulative effect of environmental factors and genetic predisposition. Although several risk loci have been already identified, HP bio...

Descrición completa

Detalles Bibliográficos

Principais autores:	Flavio De Angelis, Oana A. Zeleznik, Frank R. Wendt, Gita A. Pathak, Daniel S. Tylee, Antonella De Lillo, Dora Koller, Brenda Cabrera-Mendoza, Royce E. Clifford, Adam X. Maihofer, Caroline M. Nievergelt, Gary C. Curhan, Sharon G. Curhan, Renato Polimanti
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2023-05-01
Series:	Genome Medicine
Assuntos:	Hearing problems Genome-wide association study Ancestry; Polygenic risk scores Transcriptomic regulation Sex differences Pleiotropy
Acceso en liña:	https://doi.org/10.1186/s13073-023-01186-3
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!