Severe obesity as an oligogenic condition: evidence from 1714 adults seeking treatment in the UK National Health Service

Abstract Previous evidence has established genetics as an important contributing factor to severe (class III) obesity, which is a chronic, relapsing condition, with a high burden of comorbidity and mortality. We therefore designed a custom genotyping array to screen a cohort of UK patients seeking t...

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Autori principali:	Sumaya Almansoori, Hasnat A. Amin, Suzanne I. Alsters, Dale Handley, Andrianos M. Yiorkas, Nikman Adli Nor Hashim, Nurul Hanis Ramzi, Gianluca Bonanomi, Peter Small, Sanjay Purkayastha, Mieke van Haelst, Robin G. Walters, Carel W. le Roux, Harvinder S. Chahal, Fotios Drenos, Alexandra IF Blakemore
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2025-12-01
Serie:	Human Genomics
Accesso online:	https://doi.org/10.1186/s40246-025-00895-7
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