Genetic and stochastic influences upon tumor formation and tumor types in Li-Fraumeni mouse models
This study used mice heterozygous for Tp53 mutations with different genetic backgrounds to investigate the genetic or stochastic factors that modify the penetrance of tumor formation by Tp53 mutation. p53 is the most frequently mutated gene in human cancers. Li-Fraumeni syndrome patients inheriting...
সংরক্ষণ করুন:
| প্রধান লেখক: | , , , , , , , , |
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| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
Life Science Alliance LLC
2021-03-01
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| মালা: | Life Science Alliance |
| অনলাইন ব্যবহার করুন: | https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202000952 |
| ট্যাগগুলো: |
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