Lifestyle Intervention Therapy Modulates Global DNA Methylation and Adipogenic Gene Expression in Severely Obese Hypogonadal Men

<b>Background/Objectives:</b> Previous studies have suggested that lifestyle intervention (LSI) therapies involving diet and exercise can modulate DNA methylation; however, whether this occurs in severely obese hypogonadal men undergoing weight loss from diet and exercise remains unclear. <b>Methods...

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Hauptverfasser:	Siresha Bathina, Virginia Fuenmayor Lopez, Mia Prado, Salina Biene Teo, Dennis T. Villareal, Rui Chen, Clifford Qualls, Reina Armamento-Villareal
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2026-03-01
Schriftenreihe:	Metabolites
Schlagworte:	obesity hypogonadism lifestyle intervention DNA methylation
Online-Zugang:	https://www.mdpi.com/2218-1989/16/3/198
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