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A PRDM16-driven signal regulates body composition in testosterone-treated hypogonadal men

BackgroundTestosterone (T) therapy increases lean mass and reduces total body and truncal fat mass in hypogonadal men. However, the underlying molecular mechanisms for the reciprocal changes in fat and lean mass in humans are not entirely clear.MethodsSecondary analysis of specimens obtained from a...

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Auteurs principaux: Siresha Bathina, Georgia Colleluori, Dennis T. Villareal, Lina Aguirre, Rui Chen, Reina Armamento-Villareal
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2024-09-01
Collection:Frontiers in Endocrinology
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Accès en ligne:https://www.frontiersin.org/articles/10.3389/fendo.2024.1426175/full
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