Computer-aided Discovery of Novel COX-2 Inhibitors for Anti-inflammatory Therapy Using Pharmacophore Modelling, Molecular Docking, ADMET, and Virtual Screening

Cyclooxygenase-2 (COX-2) is a central enzyme in inflammation and a validated target for anti-inflammatory drug development. However, many existing COX-2 inhibitors cause gastrointestinal and cardiovascular side effects, necessitating safer alternatives. This study employed a computer-aided drug dis...

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Principais autores:	Usama Yousafzai, Najia Javed, Syed Luqman Ali, Awais Ali, Amir Hamza
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cultech Publishing Sdn. Bhd. 2025-12-01
Colecção:	Advances in Modern Biomedicine
Assuntos:	Tanshinone IA, COX-2 Inhibitors, Pharmacophore Modelling, Molecular Docking, Anti-inflammatory therapy
Acesso em linha:	https://amb.cultechpub.com/amb/article/view/29
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