Gut microbial bile salt hydrolase as a metabolic gatekeeper in digestive homeostasis and disease

The gut microbiota exerts broad control over host physiology through tightly coordinated metabolic networks. Among these, bile salt hydrolase (BSH), a microbial enzyme, serves as a key mediator of microbiota–host crosstalk. As a key upstream gateway reaction in bile acid metabolism, BSH hydrolyzes c...

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Hlavní autoři:	Haitao Chu, Xin Song, Chang Liu, Tianjiao Ma, Wanlin Cui
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2026-06-01
Edice:	Frontiers in Immunology
Témata:	bile acid metabolism BSH digestive diseases gut microbiota gut–liver axis microbiota-based therapy
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1870619/full
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